PhD studentship award: Problem behaviours in Tuberous Sclerosis Complex

Grant holder: Professor Chris Oliver (Stacey Bissell)
: Cerebra Centre for Neurodevelopmental Disorders, University of Birmingham

Project status: Completed – Sept 2017

The proposed PhD will address problem behaviours shown by individuals with Tuberous Sclerosis Complex. The ultimate aim of this programme of work will be to develop an early intervention and systematic assessment strategy where the most at risk children can be identified and signposted towards the most appropriate intervention (treatment of pain, communication training, training to improve ability to wait, environmental changes etc.). It is also anticipated that the project will develop and trial methods to evaluate ‘readiness’ for such intervention (e.g. functional communication training, delay of gratification training). The problem behaviours of interest include self-injury, aggression and temper outbursts. There will be a specific focus in one aspect of the project on potential roles of internal states (including pain/discomfort, seizures and poor sleep) in influencing the behaviour of less able individuals where self-report is not possible.

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