Fellowship award: Autism Spectrum and ADHD in the TSC 2000 Cohort Study

Grant holder: Professor Patrick Bolton  
: Dr Holan Liang Institute of Psychiatry, Kings College London

Project status: Ongoing – no cost extension granted until 31 Dec 2018.

Individuals with TS are at increased risk for developing both autism spectrum disorders (ASD) and Attention Deficit Hyperactivity disorder (ADHD). However, the reasons for the increased risks are very poorly understood. Evidence from studies of individuals without TS who have ASD and / or ADHD indicate that there are both shared and distinct risk factors for each condition. The prevalence, comorbidity, correlates and risk factors for ASD and ADHD are being examined in a study called TS 2000.

The TS 2000 study is the first comprehensive longitudinal study of TS with over 140 families participating nationwide. In phase one, the study recruited children as soon as possible after diagnosis of TS in order to collect good quality data on their early development. Phase two aims to follow-up everyone in TS 2000 to see how they have been progressing since they were originally assessed.

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